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News from the BMJ

BMJ 2003;327 (16 August)
Use of NSAIDs in pregnancy increases risk of miscarriage

Using non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, during pregnancy increases the risk of miscarriage.

BMJ 2003;327:360 (16 August)
Officials warn of multiple drug resistance in the community
Roger Dobson, Abergavenny

Bacteria with multiple resistance to antibiotics, until now found only in UK hospitals, may have emerged in the community.

Samples taken from 57 patients, mostly with urinary tract infections, in two parts of the United Kingdom, have shown evidence of Escherichia coli with multiple resistance to drugs.

BMJ 2003;327:360 (16 August)
Indian government faces court battle over antiretrovirals
Sanjay Kumar, New Delhi

A non-governmental organisation, the Punjab Voluntary Health Association, has dragged the Indian government and the National AIDS Control Organisation to the Supreme Court in a public interest writ over depriving AIDS patients of antiretroviral drugs in government hospitals, effectively leaving them to die.

BMJ 2003;327:360 (16 August)
Libyan government lets AIDS experts comment on hospital deaths
Katka Krosnar, Prague

Fears remain that 16 medical workers accused of deliberately infecting almost 400 Libyan children with HIV could be sentenced to death if convicted.

BMJ 2003;327:357 (16 August)
Cabinet rules that South Africans must be given antiretrovirals
Pat Sidley, Johannesburg

The South African cabinet announced at the end of last week that it has ordered the health minister, Dr Manto Tshabalala-Msimang, to compile a plan for the roll out of antiretroviral treatment for people with HIV and AIDS.

BMJ 2003;327 (9 August)
Short interpregnancy interval is associated with adverse outcome

Conceiving shortly after giving birth is independently associated with preterm birth and neonatal death.

BMJ 2003;327:306 (9 August)
South African government to withdraw antiretrovirals for pregnant mothers
Pat Sidley, Johannesburg

South Africa’s first AIDS conference got off to a painful start last weekend. At the opening of the conference, AIDS activists stood in silent protest at the health minister, Dr Manto Tshabalala Msimang, while others booed her loudly.

BMJ 2003;327:245 (2 August 2003)
HIV cases rising sharply in India
Sanjay Kumar, New Delhi

India has seen a sharp increase in the reported number of people who are HIV positive, according to the new estimates for 2002 released by India’s National AIDS Control Organisation.

BMJ 2003;327:245 (2 August 2003)
Liberia faces a humanitarian catastrophe, warn aid agencies
Peter Moszynski, London

Humanitarian agencies are warning that cholera and dysentery could be out of control as conditions deteriorate in Liberia’s beleaguered capital, Monrovia. A rebel assault on the city that has killed hundreds of civilians has left hundreds of thousands more without access to food or clean water.

BMJ 2003;327 (2 August 2003)
Vitamin A given soon after birth increases survival of newborns

Giving newborn infants vitamin A soon after birth can reduce mortality before 6 months of age by over 20%.

BMJ 2003;327:182 (26 July)
EU commits $1bn to global fund
Alexander Dorozynski, Paris

The president of the European Commission, Romano Prodi, guaranteed a European contribution of $1bn (£630m; €890m) for 2004 to the Global Fund to Fight AIDS, Tuberculosis and Malaria.

BMJ 2003;327:184 (26 July)
More than half of male medical students don’t practise safe sex on holiday
Roger Dobson, Abergavenny

Medical students on holiday are not setting an example for safer sex. According to a survey, fewer than half of male students who have sex with a new partner when on holiday always use a condom.

BMJ 2003;327:184 (26 July)
Food emergency looms in war torn Sudan
Peter Moszynski, London

The UN World Food Programme has warned that a serious funding shortfall, despite growing evidence of a food emergency, may lead to cuts in food distribution in Sudan.

BMJ 2003;327:184 (26 July)
Free retroviral drugs could save up to 1.7 million South Africans
Pat Sidley, Johannesburg

By offering free antiretroviral drugs to the six million people with HIV/AIDS who can’t afford them the South African government could save or prolong the lives of about 1.7 million people, a new study says.

BMJ 2003;327 (26 July)
Patients in Uganda prefer to die at home

A good death in developing countries like Uganda, where resources are scarce, occurs when the dying person is being cared for at home, is free from pain and other distressing symptoms, feels no stigma, and is at peace.

BMJ 2003;327 (19 July)
Girls are less likely to survive infancy in India

In India more female infants than male infants die from easily treatable conditions. In a retrospective analysis of verbal autopsies collected by health workers in three Delhi slums, Khanna and colleagues (p 126) found an excess number of deaths among girls due to conditions such as diarrhoea. There were no significant differences in deaths due to less preventable and less treatable conditions like birth asphyxia. Three quarters of the unexplained infant deaths, for which no history of illness and no sufficient explanation were found, were in girls. In India, where there are more men than women, the role of sex discrimination is of wide concern; both antenatal sex determination and female feticide are incriminated.

BMJ 2003;327 (19 July)
First WHO treaty tackles international tobacco control

Tobacco control requires international collaboration and action, but getting governments to agree on strategies is difficult. Shibuya and colleagues (p 154) describe the development of the WHO’s Framework Convention on Tobacco Control, an evidence based global public health treaty that was endorsed by member states on 21 May 2003. It represents the first time that WHO has used its constitutional authority to develop a legal instrument for improving health. Drawing on scientific evidence, the convention includes measures relating to reducing the demand for tobacco (price and tax measures, restrictions on tobacco advertising) and the supply of tobacco (restriction of sales to minors, economically viable alternatives for growers). The authors state that these interventions could reduce the global burden of disease attributable to tobacco by up to 60%.

BMJ 2003;327:120 (19 July)
Lords committee warns of gaps in infection control measures
Lynn Eaton, London

England has a shortage of appropriately trained experts in identifying infectious diseases, says a report published this week by the House of Lords.

BMJ 2003;327:124 (19 July)
HIV testing should not be used to restrict access to UK, report says
Debashis Singh, London

Testing migrants and asylum seekers for HIV at the point of entry into the United Kingdom to restrict access into the country and to medical services would achieve little more than to stigmatise HIV further, a report from the All-Party Parliamentary Group on AIDS said last week.

BMJ 2003;327:124 (19 July)
WHO report calls for free anti-tuberculosis drugs for AIDS patients
Fiona Fleck, Geneva

A new report by the World Health Organization in the style of a glossy but hard hitting brochure aims to draw attention to the global tuberculosis epidemic that has been spurred by the spread of HIV and multidrug resistant tuberculosis strains.

BMJ 2003;327:122 (19 July)
AIDS will affect us all eventually, Mandela tells London audience
Daloni Carlisle, London

Nelson Mandela has called for a new war against HIV/AIDS, arguing that it is claiming more lives in Africa than the sum total of all wars, famines, floods, and other deadly diseases, such as malaria.

BMJ 2003;327:124 (19 July)

Anne Gulland, London

Researchers hope to see the first results from the largest ever malaria vaccine trial in children in Africa in just 18 months, the research team leader announced last week.

BMJ 2003;327:124 (19 July)
Africa has a right to support from international community in its fight against HIV/AIDS, malaria, and tuberculosis
Harry McConnell, Maputo

Africa has a right to demand support from the international community in its fight against AIDS, tuberculosis, malaria and other diseases, Professor Jeffrey Sachs, executive director of the Earth Institute at Columbia University, told a meeting of African heads of state in Maputo, Mozambique last week.

BMJ 2003;327 (12 July)
Women need full information for breast screening decisions

The value of routine mammography is debated, but women must be the ones to make informed choices about the screening examination. Thornton and colleagues (p 101) argue that the focus of the debate in the media and among scientists on the efficacy of mammography misses the point. Women must be empowered to make individual decisions about screening, which the authors say are essentially value judgements. This can be facilitated by providing women with full information on harms and benefits, and doing so in a way that is understandable. The authors state that unless women are able to make true informed choices, support and funding for routine mammography will continue to be questioned.

BMJ 2003;327:72 (12 July)
Italian EU presidency brings ambitious health targets
Rory Watson, Brussels

The Italian government has set itself an ambitious public health agenda as it presides over European Union business for the next six months. Heading the list are moves to establish a European centre for disease prevention and control and to increase information to the public on the importance of healthy lifestyles.

BMJ 2003;327:72 (12 July)
Women in Ulster should have access to abortion services
Linda Beecham, BMJ

Representatives at the BMA’s annual conference criticised the fact that women in Northern Ireland still do not have access to the same abortion facilities as women in the rest of the United Kingdom and called on the government to rectify this anomaly.

BMJ 2003;327:10 (5 July)
Doctors fear that rise in infection rates points to a return to unsafe sex
Tony Sheldon, Utrecht

Numbers of cases of sexually transmitted infection in the Netherlands have increased by two thirds in three years, leaving researchers “alarmed” because it points to an increase in unsafe sex. The total figure for all sexually transmitted infections rose over three years from about 5500 to 9500.

BMJ 2003;327:10 (5 July)
UN report predicts shortfall in AIDS funding in developing countries
Susan Mayor, London

Funding for the prevention and treatment of AIDS in low and middle income countries is only about half what is needed to provide basic services, warned a report published by the Joint United Nations Programme on HIV/AIDS (UNAIDS) last week.

BMJ 2003;327:10 (5 July)
Unsafe sexual practices are common, say US studies
Deborah Josefson, Nebraska

Unsafe sexual practices are common in people infected with HIV and in those at high risk of infection, warned two US epidemiological studies published this week in the American Journal of Public Health. Results suggest that new preventive, educational, and public health strategies are needed to prevent HIV transmission and reduce the risk of a new AIDS epidemic.

BMJ 2003;327:11 (5 July)
Aid agency launches latest initiative to tackle diseases in the developing world
Ganapati Mudur, New Delhi

The quest for drugs to fight the world’s most neglected tropical infectious diseases gained fresh momentum with the formal launch of the “drugs for neglected diseases” initiative this week.

BMJ 2003;327:12 (5 July)
US scientists back bill for free access to publicly funded science research
Janice Hopkins Tanne, New York

A star studded group of US doctors and scientists is supporting legislation for publicly funded research to be made available free by “open access” on the internet, an initiative spearheaded by the Public Library of Science, a non-profit organisation (www.plos.org).

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